Erectile and sexual health
When Erection Tablets Stop Working: What Should I Do Next?
A change in response is a reason to review how treatment is used and your wider health, with several possible routes forward.

Clinically reviewed by Dr Paul Thomas, BMBS, BMedSci (Hons), MRCGP
GP and Medical Director, Oxfordshire Men's Health · GMC 7562376
Clinically reviewed 16 October 2026 · 5 min read
If erection tablets used to help but now seem unreliable, it is worth arranging a review. An occasional disappointing response does not establish that treatment has permanently stopped working.
The next step is to look at what has changed: how the medicine is being used, your health, other medication and the circumstances around sex. Increasing the dose yourself can add risk without addressing the cause.
Start with what “not working” means
Try to describe the change as precisely as you can. Is it harder to get an erection, keep it, or both? Does the problem happen every time or only in certain situations? Has sexual desire changed too?
Tell the clinician whether the tablets ever worked reliably, when the change began and whether you still notice spontaneous or morning erections. These details help guide assessment, but no single answer proves a physical or psychological cause.
A short note of a few recent occasions can be useful. You do not need to turn intimacy into a performance test.
Check how you are using the medicine
Before deciding that a treatment has failed, a clinician should check the prescription, the source of the medicine and how it is taken.
Timing matters. Food can delay the effect of some erection tablets, and sexual stimulation is still needed. The instructions differ between medicines, so follow the directions for your own prescription rather than advice intended for another product.
Bring the packaging or a photograph of its label. Explain when you take it, whether you take it with food, and whether side effects have led you to use it differently. A pharmacist can help clarify the instructions.
Do not take extra doses, combine erection medicines or add online “boosters” without medical advice.
Could something have changed in my general health?
Persistent erection problems can be associated with diabetes, high blood pressure, high cholesterol, medication effects, depression or anxiety. Alcohol, tiredness and stress can also affect erections.
A review may therefore include blood pressure and an assessment of cardiovascular risk, alongside questions about sleep, smoking, activity and recent health changes. Relevant blood tests may be considered, including glucose or HbA1c, lipids and testosterone.
This does not mean every man needs an extensive test panel, or that reduced response automatically indicates heart disease or low testosterone. The purpose is to look for contributors that can be addressed.
Do not stop other prescribed medicines yourself. If one might be contributing, discuss alternatives with the clinician responsible for it.
What about confidence, stress and relationships?
After an unexpected difficulty, it is understandable to worry about the next time. That pressure can become part of the problem even when there is also a physical cause.
Discussing this is a normal part of medical care. Psychological support or psychosexual therapy may be useful alongside physical assessment and treatment. It does not imply that the symptoms are imagined.
You can attend alone or involve a partner if you wish. Let the clinician know what you are comfortable discussing and what outcome matters to you.
What options are available if tablets remain unsuitable or ineffective?
After reviewing correct use and possible causes, the clinician may discuss a different treatment approach. This might involve adjusting prescribed treatment, a vacuum erection device, psychosexual support or referral for specialist options. Selected patients may consider other medicines administered locally or surgery following specialist assessment.
The choice depends on effectiveness, safety, preferences and the underlying problem. Treatments involving procedures need a discussion of their evidence, risks and alternatives; a confident marketing claim is not enough to establish benefit.
Not every option is available through every clinic. A useful consultation should explain what can be managed there and when referral would be more appropriate.
What should I bring to a review?
Bring your medication list, the name and dose of the erection treatment, any relevant test results and a brief account of what has changed. Mention new pain, penile curvature or other symptoms.
For men in Oxfordshire, our guide to private erectile dysfunction assessment explains what a GP-led consultation can involve. Oxfordshire Men’s Health is based in Fyfield, near Abingdon; current appointment availability is shown below.
You do not have to keep repeating an approach that is no longer helping. A review can clarify the problem and identify a sensible next step.
Frequently asked questions
- Does this mean tablets will never work again?
Not necessarily. A review may identify an issue with timing or use, a change in health, or another factor affecting the response. There are also other management options.
- Should I take an extra tablet if the first one does not work?
Do not exceed the prescribed dose or combine erection medicines without advice. Ask your prescriber or pharmacist to review your instructions and whether the treatment remains suitable.
- Does it mean I have low testosterone?
No. Erection difficulties have several possible causes. Hormone testing may form part of assessment, but a disappointing response to tablets does not diagnose testosterone deficiency.
- Can I bring my partner?
A partner can attend if you would find that helpful, but this is entirely your choice. You can also discuss concerns privately.
Sources and further reading
Next step
For discreet updates on appointment availability, join the private launch list. Joining does not commit you to testing or treatment.

